Panbesy should be taken no longer than 12 weeks. If you used panbesy for too long or in high does it increases the chance of addiction or withdrawals. Withdrawals may occure as depression or tiredness. That’s why don’t increase your dosage, take it too often or for long time. Especially if you have previous record of drug abuse or alcohol abuse. Don’t take other appetite suppressant with panbesy. Use panbesy in that dosage that has been prescribed by your doctor and stop to take when so directed.